What is Etizolam Powder in 2020?
Etizolam is also called Etilaam, Etizest, Desolam or street valium and broadly belongs to a category of compounds called benzodiazepines. Its sometimes called as benzodiazepine analog. It differs from a benzodiazepine in that the benzene ring of benzodiazepines has been replaced by a thiophene ring and a triazole ring has been added, thus making the drug a thienotriazolodiazepine. The molecular structure is shown here for your convenience.
Chemical Formula: C17H15ClN4S
Molecular Weight: 342.846 g/mol
IUPAC Name: 7-(2-chlorophenyl)-4-ethyl-13-methyl-3-thia-1,8,11,12-tetraazatricyclo[188.8.131.52²,⁶]trideca-2(6),4,7,10,12-pentaene
Chemistry behind the Incredible Properties of Etizolam:
Etizolam is a thienodiazepine, which chemically belongs to benzodiazepine (BDZ) drug group; it differs from BDZs in that its benzene ring is replaced with a thiophene ring. This addition induces the calming and healing properties in Etizolam adding on the sedative properties of benzodiazepines.
Other names of Etizolam:
The Most Sought after Properties
The long list of amazing psychoactive benefits includes amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties to mention a few.
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Place order of the quantity needed and leave the quality to us. Unparalleled product quality is our distinguishing feature.Etizolam has become the center of attention for psychoactive drug researchers and pharmacists because of its wondrous properties not least of which are its amnesic, anticonvulsant, hypnotic and muscle relaxant benefits. This extraordinary compound has been put to use by medical specialists for the treatment of everything from anxiety disorders and panic attacks to seizures and insomnia. Everybody seems to be interested in knowing more about Etizolam magical properties, availability, where to buy Etizolam and legality etc. We have placed it all here for you in this article, so read on to get things straight about this wonder drug.
Origin of Etizolam
Etizolam is known to have been introduced in 1983 in Japan. Initially, it was used as treatment for neurological conditions such as anxiety and sleep disorders. Etizolam is promoted as a drug in Japan, Italy and India. FDA hasn’t approved it in the US as of now; however it remains unscheduled in several states and is legal for research purposes.
Pharmacology of Etizolam
Etizolam is primarily a CNS depressant as it works by binding to the receptors in CNS, where it produces the soothing effects. It’s now prescribed for the treatment of generalized anxiety disorder with depression, panic disorder and insomnia in many regions.
Etizolam gets absorbed fairly rapidly in blood stream. The peak plasma levels are recorded to be achieved anywhere between 30 minutes and 2 hours. Etizolam works by acting as a full agonist at the benzodiazepine receptor to produce its range of therapeutic effects. Benzodiazepine receptors are part of the GABA receptor complex, which are found on postsynaptic nerve endings in the central nervous system (CNS). GABA is the primary inhibitory neurotransmitter of the CNS.
The recommended dosage known for producing positive results of the drug ranges from 0.2mg to 5mg. Normally administered dose of the drug ranges from 1-2mg whereas light doses of the drug are from 0.2mg – 1mg of concentration. A heavy dose that might produce adverse effects is greater than or equal to 5mg.
Side Effects of Etizolam
Etizolam rarely produce the full range of positive effects in recommended dosage which leads people to go for greater dose of the drug. While greater dose can cause some wanted effects but it can cause serious side effects which include severe medical conditions or death in extreme conditions.
The drug can cause a series of adverse effects when administered against the recommended dosage. Common side effects include drowsiness, sedation, muscle weakness and incoordination, fainting, headache, impaired speech, visual imparity and changes in libido.
Reversing the Side Effects:
Flumazenil works as an antagonist of GABA-A receptors and can be used to reverse the effect of Etizolam over dosage.
Legitimacy of Etizolam
The World Health Organization (WHO) recommended Etizolam for placement in Schedule 4 of the 1971 Convention on Psychotropic Substances. This led the placement of Etizolam into Schedule IV in March 2020.
Etizolam is not authorized by the FDA for medical use in the U.S. However, it currently remains unscheduled at the federal level and is legal for research purposes. Etizolam is marketed as a drug openly in some of the countries like Japan, India and Australia while most of the regions permit its use as a controlled substance. Due to possible adverse effects, it’s completely banned in some states as well.
Etizolam is undergoing extensive research but hasn’t been approved by FDA yet, because of this it’s used as a controlled substance in some places and is completely banned in other. Anybody buying must be of legal age and should hold valid reasons for its consumption.
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